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Rontalizumab (CAT#: TAB-074)

Datasheet
DESCRIPTION CATALOG # SIZE PRICE
Anti-Human IFN alpha Recombinant Antibody TAB-074 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • Recombinant monoclonal antibody to IFN alpha. Rontalizumab is a humanized monoclonal antibody. for treatment of systemic lupus erythematosus.
  • Target
  • IFN alpha
  • Type
  • IgG1 - kappa
  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Species Reactivity
  • Human
  • Expression Host
  • CHO
  • Applications
  • Suitable for use in ELISA, FC, IP, FuncS, IF, Neut, ICC and most other immunological methods.
  • CAS
  • 948570-30-7
  • Specific Activity
  • Tested positive against native human antigen.
  • Protein Construction
  • Immunoglobulin G1-kappa, anti-[Homo sapiens interferon alpha (IFN-alpha)], humanized monoclonal antibody; gamma1 heavy chain [humanized VH (Homo sapiens IGHV3-74*01(76.30%) -(IGHD)-IGHJ4*01) [8.8.10] (1-117) -Homo sapiens IGHG1*03, CH1 R120>K (118-447)], (220-218")-disulfide with kappa light chain (1"-218") [humanized V-KAPPA (Homo sapiens IGKV1-39*01 (83.80%) -IGKJ1*01) [10.3.9] (1"-111") -Homo sapiens IGKC*01 (112"-218")]; (226-226":229-229")-bisdisulfide dimer
  • Predicted N terminal
  • H Chain: EVQLVES; L Chain: DIQMTQS
  • Molecular Weight
  • 145900
  • Purity
  • >95.0%, determined by analysis by RP-HPLC & analysis by SDS-PAGE.
  • Size
  • 1mg
  • Storage
  • Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.

BACKGROUND

  • Antigen Description
  • Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
  • Synonyms
  • IFNA1; interferon, alpha 1; interferon alpha-1/13; IFL; IFN; IFN ALPHA; IFN alpha 1b; IFN alphaD; IFNA13; IFNA@; interferon alpha 1b; leIF D; IFN-alpha 1b; IFN-alpha-1/13; interferon-alpha1; interferon alpha-D; IFN-ALPHA; IFN-alphaD; MGC138207; MGC138505; MGC138507;

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